12 Jun

People of old age suffer from a lot of cognitive disorders with Parkinson’s and Alzheimer’s disease being two of the most common ones.

The prevalence of people who suffer from such increases because of the fact that as we age, our brain’s ability to produce new neurons naturally decline.

In a report published back on March 5th, scientists have found that the gene, Dbx2, is actually one of the factors that can contribute to the functional decline of neural stem cells in mice as they age.

The Research

So, the scientists compared both the neurons of young mice and that of the old mice and they found that the said gene (Dbx2) is present in the older mice.

After that, the researchers would extract neural stem cells from the brains of the younger mice and then it would be transplanted into the brains of the older mice and they’ve discovered that the Dbx2 gene did fire up when there is a presence of new neural stem cells.

Peter Rugg-Gunn, a stem cell biologist at the Babraham Institute, issued a press release stating that by doing this experiment, they can better understand how aging can affect the brain.

Although the study was conducted on mice, it is somewhat safe to say that the same phenomenon could also be true in humans. This was done in order for us to truly know what causes cognitive decline as we age.
In conclusion, the Dbx2 gene has an effect when it comes to the decline of our cognition as we reach old age.